What it's used for
Famotidine is used to treat active duodenal ulcers, active gastric ulcers, symptomatic nonerosive gastroesophageal reflux disease, and erosive esophagitis.
Source: U.S. FDA-approved prescribing information (openFDA).
Typical dosing
Adult and pediatric patients 40 kg and greater typically take 20 mg to 40 mg once or twice daily depending on the specific condition being treated.
Dosing shown here is the general FDA-labeled range. Your prescribing clinician determines the exact dose, form, and schedule for you — this is not a substitute for medical advice.
Common side effects
The most common adverse reactions include headache, dizziness, constipation, and diarrhea.
Covered strengths on the Tab $0 list
Covered at $0 with an active Tab membership when filled at a participating pharmacy nationwide or through mail order. A licensed clinician must prescribe the medication.
Related medications
Other everything else medications covered at $0 with an active Tab membership.
Famotidine cost without insurance
Cash prices for Famotidine without insurance vary widely by pharmacy, strength and quantity — the same prescription can cost very different amounts at two pharmacies in the same town. That is the problem a membership solves.
Famotidine is on Tab's covered $0 generic list. With an active Tab membership, every covered strength is $0 — not a percentage off, not a coupon that changes month to month — at participating pharmacies nationwide or through mail order. You do not need insurance, and Tab works whether or not you have a health plan.
Tab is a membership, not insurance. Covered medications require a prescription from a licensed clinician.
Famotidine dosage and administration
Indication Recommended Dosage ( 2.1 ) Adult and Pediatric Patients 40 kg and greater Active DU 40 mg once daily; or 20 mg twice daily Active Gastric Ulcer 40 mg once daily GERD 20 mg twice daily Erosive Esophagitis 20 mg twice daily; or 40 mg twice daily Adults Pathological Hypersecretory Conditions 20 mg every 6 hours; adjust to patient needs; maximum 160 mg every 6 hours Risk Reduction of DU Recurrence 20 mg once daily • See full prescribing information for complete dosing information, including dosing in renal impairment, and recommended treatment duration. ( 2.1 , 2.2 ) Administration ( 2.3 ): • Take once daily before bedtime or twice daily in the morning and before bedtime with or without food.
Excerpt from the FDA-approved prescribing information (openFDA), retrieved 2026-09-15. Your prescribing clinician decides the exact dose, form and schedule for you — this is not medical advice.
Famotidine side effects
The most common adverse reactions are: headache, dizziness, constipation, and diarrhea. ( 6.1 ) To report SUSPECTED ADVERSE REACTIONS, contact Annora Pharma Private Limited at 1-866-495-1995 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch. 6.1 Clinical Trial Experience Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice. Famotidine was studied in 7 US and international placebo- and active-controlled trials in approximately 2500 patients [see Clinical Studies ( 14 )].
Excerpt from the FDA-approved prescribing information (openFDA), retrieved 2026-09-15. This is not a complete list. Report side effects to your clinician, and seek care for anything severe or unexpected.
Famotidine drug interactions
• Drugs Dependent on Gastric pH for Absorption: Systemic exposure of the concomitant drug may be significantly reduced leading to loss of efficacy. See full prescribing information for a list of interacting drugs. ( 7.1 ) • Tizanidine (CYP1A2) Substrate: Potential for substantial increases in blood concentrations of tizanidine resulting in hypotension, bradycardia or excessive drowsiness; avoid concomitant use, if possible. ( 7.2 ) 7.1 Drugs Dependent on Gastric pH for Absorption Famotidine can reduce the absorption of other drugs, due to its effect on reducing intragastric acidity, leading to loss of efficacy of the concomitant drug. Concomitant administration of famotidine with dasatinib, delavirdine mesylate, cefditoren, and fosamprenavir is not recommended.
Excerpt from the FDA-approved prescribing information (openFDA), retrieved 2026-09-15. Tell your clinician and pharmacist about every medication, supplement and over-the-counter product you take.
Who should not take famotidine
Famotidine tablets are contraindicated in patients with a history of serious hypersensitivity reactions (e.g., anaphylaxis) to famotidine or other histamine-2 (H 2 ) receptor antagonists. History of serious hypersensitivity reactions (e.g., anaphylaxis) to famotidine or other H 2 receptor antagonists. ( 4 )
Excerpt from the FDA-approved prescribing information (openFDA), retrieved 2026-09-15. Whether this medication is appropriate for you is a clinical decision made by your prescribing clinician.
Common questions
Is famotidine covered at $0 with Tab?
Yes. Famotidine is on Tab's covered $0 generic list — every covered strength is $0 with an active membership, at participating pharmacies nationwide or by mail order.
Do I need insurance to get famotidine through Tab?
No. Tab is a membership, not insurance. Covered medications are $0 with an active membership whether or not you have a health plan.
How do I get a famotidine prescription with Tab?
Book a video visit with a licensed Tab clinician (unlimited visits are included with membership). If it's clinically appropriate, they send the prescription to your chosen participating pharmacy or by mail order.
How much does famotidine cost without insurance?
Without insurance, retail cash prices for famotidine vary by pharmacy, strength and quantity. Famotidine is on Tab's covered $0 generic list, so every covered strength is $0 with an active Tab membership at participating pharmacies nationwide or by mail order.
What is the cheapest way to get famotidine?
For medications on Tab's covered list, a Tab membership is the cheapest route: covered strengths of famotidine are $0 with an active membership, and unlimited video visits with a licensed clinician are included, so the visit that produces the prescription is covered too.
What is the usual dose of famotidine?
Indication Recommended Dosage ( 2.1 ) Adult and Pediatric Patients 40 kg and greater Active DU 40 mg once daily; or 20 mg twice daily Active Gastric Ulcer 40 mg once daily GERD 20 mg twice daily Erosive Esophagitis 20 mg twice daily; or 40 mg twice daily Adults Pathological Hypersecretory Conditions 20 mg every 6 hours; adjust to patient needs; (FDA-approved label, retrieved 2026-09-15. Your clinician sets your dose.)
What are the side effects of famotidine?
The most common adverse reactions are: headache, dizziness, constipation, and diarrhea. ( 6.1 ) To report SUSPECTED ADVERSE REACTIONS, contact Annora Pharma Private Limited at 1-866-495-1995 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch. (FDA-approved label, retrieved 2026-09-15.)
What interacts with famotidine?
• Drugs Dependent on Gastric pH for Absorption: Systemic exposure of the concomitant drug may be significantly reduced leading to loss of efficacy. See full prescribing information for a list of interacting drugs. ( 7.1 ) • Tizanidine (CYP1A2) Substrate: Potential for substantial increases in blood concentrations of tizanidine resulting in hypotension, bradycardia or excessive drowsiness; (FDA-approved label, retrieved 2026-09-15. Tell your clinician about every medication and supplement you take.)
Famotidine is $0 on the covered list
Members pay $0 for covered generics at participating pharmacies nationwide or by mail order — plus unlimited virtual primary care, urgent care and dermatology visits. No insurance needed.
Solo $49/mo · Family $119/mo for up to 4 people · Family+ $149/mo for up to 8
Start your membership → Compare plansTab is a membership and prescription-discount program, not insurance. A licensed clinician must prescribe any medication. Cancel anytime — no renewal.