Tab ← All covered medications
Everything else

Methotrexate

Methotrexate is a covered generic medication on Tab's $0 list. Here's what it's used for, typical dosing, and side effects, sourced from FDA-approved drug labeling.

$0 with active Tab membership Oral

What it's used for

Methotrexate tablets are used to treat adults and children with acute lymphoblastic leukemia, mycosis fungoides, non-Hodgkin lymphoma, rheumatoid arthritis, and juvenile idiopathic arthritis. They are also used to treat adults with severe psoriasis.

Source: U.S. FDA-approved prescribing information (openFDA).

Typical dosing

Dosing varies by condition, such as 20 mg per square meter orally once weekly for acute lymphoblastic leukemia or 25 to 75 mg orally once weekly for mycosis fungoides. Pregnancy status must be verified before starting treatment.

Dosing shown here is the general FDA-labeled range. Your prescribing clinician determines the exact dose, form, and schedule for you — this is not a substitute for medical advice.

Boxed warning / key safety info

Methotrexate can cause embryo-fetal toxicity, including fetal death, and is contraindicated in pregnancy for non-neoplastic diseases.

Common side effects

Clinically significant adverse reactions include hypersensitivity reactions, bone marrow suppression, gastrointestinal toxicity, and liver toxicity.

Covered strengths on the Tab $0 list

Methotrexate 2.5mg Tablet

Covered at $0 with an active Tab membership when filled at a participating pharmacy nationwide or through mail order. A licensed clinician must prescribe the medication.

Related medications

AcebutololAcetaminophenAcetazolamideAlendronate SodiumAllopurinolAmantadine

Other everything else medications covered at $0 with an active Tab membership.

See the full covered list. Find yours in seconds.

Search all medications →
Tab is a membership and prescription-discount program—not insurance, and not a substitute for it. $0 pricing applies to medications on the current covered generic list with active membership, at participating pharmacy locations nationwide or through mail order, and is subject to change. Mail-order home delivery is preferred for recurring prescriptions; activation, availability, and delivery timing apply. This page is for general reference, drawn from FDA-approved drug labeling, and is not medical advice. Only a licensed clinician can determine if a medication is right for you.