What it's used for
Diphenhydramine is used to temporarily relieve symptoms due to the common cold, hay fever, or other upper respiratory allergies such as runny nose, sneezing, itchy nose or throat, and itchy, watery eyes.
Source: U.S. FDA-approved prescribing information (openFDA).
Typical dosing
Adults and children 12 years and older take 1 caplet every 4 to 6 hours while symptoms persist, up to a maximum of 6 caplets in 24 hours.
Dosing shown here is the general FDA-labeled range. Your prescribing clinician determines the exact dose, form, and schedule for you — this is not a substitute for medical advice.
Boxed warning / key safety info
Do not use this product with any other products containing diphenhydramine, even one used on the skin.
Common side effects
See full FDA prescribing information for the complete adverse reaction profile.
Covered strengths on the Tab $0 list
Covered at $0 with an active Tab membership when filled at a participating pharmacy nationwide or through mail order. A licensed clinician must prescribe the medication.
Related medications
Other allergy, cough & cold medications covered at $0 with an active Tab membership.
Diphenhydramine cost without insurance
Cash prices for Diphenhydramine without insurance vary widely by pharmacy, strength and quantity — the same prescription can cost very different amounts at two pharmacies in the same town. That is the problem a membership solves.
Diphenhydramine is on Tab's covered $0 generic list. With an active Tab membership, every covered strength is $0 — not a percentage off, not a coupon that changes month to month — at participating pharmacies nationwide or through mail order. You do not need insurance, and Tab works whether or not you have a health plan.
Tab is a membership, not insurance. Covered medications require a prescription from a licensed clinician.
Diphenhydramine dosage and administration
Directions ■ if needed, take every 4-6 hours ■ do not take more than 6 doses in 24-hours children under 4 years of age Do not use children 4 to under 6 years of age Do not use unless directed by a doctor children 6 to under 12 years of age 1 to 2 teaspoonfuls (5 ml to 10 ml)
Excerpt from the FDA-approved prescribing information (openFDA), retrieved 2026-09-15. Your prescribing clinician decides the exact dose, form and schedule for you — this is not medical advice.
Common questions
Is diphenhydramine covered at $0 with Tab?
Yes. Diphenhydramine is on Tab's covered $0 generic list — every covered strength is $0 with an active membership, at participating pharmacies nationwide or by mail order.
Do I need insurance to get diphenhydramine through Tab?
No. Tab is a membership, not insurance. Covered medications are $0 with an active membership whether or not you have a health plan.
How do I get a diphenhydramine prescription with Tab?
Book a video visit with a licensed Tab clinician (unlimited visits are included with membership). If it's clinically appropriate, they send the prescription to your chosen participating pharmacy or by mail order.
How much does diphenhydramine cost without insurance?
Without insurance, retail cash prices for diphenhydramine vary by pharmacy, strength and quantity. Diphenhydramine is on Tab's covered $0 generic list, so every covered strength is $0 with an active Tab membership at participating pharmacies nationwide or by mail order.
What is the cheapest way to get diphenhydramine?
For medications on Tab's covered list, a Tab membership is the cheapest route: covered strengths of diphenhydramine are $0 with an active membership, and unlimited video visits with a licensed clinician are included, so the visit that produces the prescription is covered too.
What is the usual dose of diphenhydramine?
Directions ■ if needed, take every 4-6 hours ■ do not take more than 6 doses in 24-hours children under 4 years of age Do not use children 4 to under 6 years of age Do not use unless directed by a doctor children 6 to under 12 years of age 1 to 2 teaspoonfuls (5 ml to 10 ml) (FDA-approved label, retrieved 2026-09-15. Your clinician sets your dose.)
Diphenhydramine is $0 on the covered list
Members pay $0 for covered generics at participating pharmacies nationwide or by mail order — plus unlimited virtual primary care, urgent care and dermatology visits. No insurance needed.
Solo $49/mo · Family $119/mo for up to 4 people · Family+ $149/mo for up to 8
Start your membership → Compare plansTab is a membership and prescription-discount program, not insurance. A licensed clinician must prescribe any medication. Cancel anytime — no renewal.